3D visualisation of annotations from Phase 1.


We are excited to announce that we have launched a new workflow on Science Scribbler!

We launched Science Scribbler: Phase 1 last year. Over 1000 citizen scientists have volunteered to annotate the subcellular structure (organelles) inside a cell! With your contribution, the annotation process that would take a researcher approximately a year was completed within a few months. Thank you very much to those who have been involved in our project. You can see more results from the project so far here – www.zooniverse.org/projects/msbrhonclif/science-scribbler/about/results.

The next step of the project is to analyse the annotated data to answer whether there is any change in the subcellular structure (organelles) in Huntington’s disease. The first step in doing this is to clean up the raw data. Annotation is a complicated and difficult task since there are different types of organelles with various intensities, sizes and shapes. In addition, differentiating the object (organelle) from the background (non-organelle) is particularly difficult in gray scale images due to a low signal-to-noise ratio. Because of this, there is variability and subjectivity in the original annotation data we collected. Before analysing this raw data, we would like to clean it up so that we can answer the biological questions more accurately and correctly.

This is where we need your help! In order to overcome the variability associated with the original annotations, we need your help to ensure a consensus emerges! Please help us by visiting www.zooniverse.org/projects/msbrhonclif/science-scribbler today to get started!

You can also take part using the Zooniverse mobile app. Just download the app from the Google Play Store or Apple App Store and you’ll find Science Scribbler under the ‘Medicine’ section.